Ontology highlight
ABSTRACT:
SUBMITTER: Petris G
PROVIDER: S-EPMC4011882 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Petris Gianluca G Bestagno Marco M Arnoldi Francesca F Burrone Oscar R OR
PloS one 20140506 5
Monoclonal antibodies (mAbs), because of their unique specificity, are irreplaceable tools for scientific research. Precise mapping of the antigenic determinants allows the development of epitope tagging approaches to be used with recombinant proteins for several purposes. Here we describe a new family of tags derived from the epitope recognized by a single highly specific mAb (anti-roTag mAb), which was obtained from a pool of mAbs reacting with the rotavirus nonstructural protein 5 (NSP5). The ...[more]