N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation.
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ABSTRACT:
SUBMITTER: Bateman LA
PROVIDER: S-EPMC6223258 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Publications
N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation.
Bateman Leslie A LA Zaro Balyn W BW Chuh Kelly N KN Pratt Matthew R MR
Chemical communications (Cambridge, England) 20121212 39
Metabolic chemical reporters of glycosylation allow for the visualization and identification of a variety of glycoconjugates by taking advantage of the promiscuity of carbohydrate metabolism. Here we describe the synthesis and characterization of metabolic chemical reporters bearing an N-propargyloxycarbamate (Poc) group that creates discrimination between glycosylation pathways. ...[more]
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