Postoperative delirium in a substudy of cardiothoracic surgical patients in the BAG-RECALL clinical trial.

ABSTRACT:

Background

Postoperative delirium in the intensive care unit (ICU) is a frequent complication after cardiac or thoracic surgery and is associated with increased morbidity and mortality.

Methods

In this single-center substudy of the BAG-RECALL trial (NCT00682825), we screened patients after cardiac or thoracic surgery in the ICU twice daily for delirium using the Confusion Assessment Method for the ICU. The primary outcome was the incidence of delirium in patients who had been randomized to intraoperative Bispectral Index (BIS)-guided and end-tidal anesthetic concentration-guided depth of anesthesia protocols. As a secondary analysis, a Bayesian stochastic search variable selection strategy was used to rank a field of candidate risk factors for delirium, followed by binary lo

SUBMITTER: Whitlock EL 

PROVIDER: S-EPMC4012920 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature