Ontology highlight
ABSTRACT:
SUBMITTER: Leung JM
PROVIDER: S-EPMC5605447 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Leung Jacqueline M JM Sands Laura P LP Chen Ningning N Ames Christopher C Berven Sigurd S Bozic Kevin K Burch Shane S Chou Dean D Covinsky Kenneth K Deviren Vedat V Kinjo Sakura S Kramer Joel H JH Ries Michael M Tay Bobby B Vail Thomas T Weinstein Philip P Chang Stacey S Meckler Gabriela G Newman Stacey S Tsai Tiffany T Voss Vanessa V Youngblom Emily E
Anesthesiology 20171001 4
<h4>Background</h4>Postoperative pain and opioid use are associated with postoperative delirium. We designed a single-center, randomized, placebo-controlled, parallel-arm, double-blinded trial to determine whether perioperative administration of gabapentin reduced postoperative delirium after noncardiac surgery.<h4>Methods</h4>Patients were randomly assigned to receive placebo (N = 347) or gabapentin 900 mg (N = 350) administered preoperatively and for the first 3 postoperative days. The primary ...[more]