Exploiting fast detectors to enter a new dimension in room-temperature crystallography.

ABSTRACT: A departure from a linear or an exponential intensity decay in the diffracting power of protein crystals as a function of absorbed dose is reported. The observation of a lag phase raises the possibility of collecting significantly more data from crystals held at room temperature before an intolerable intensity decay is reached. A simple model accounting for the form of the intensity decay is reintroduced and is applied for the first time to high frame-rate room-temperature data collection.

SUBMITTER: Owen RL 

PROVIDER: S-EPMC4014120 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature