Ontology highlight
ABSTRACT:
SUBMITTER: Hensbergen PJ
PROVIDER: S-EPMC4014281 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Hensbergen Paul J PJ Klychnikov Oleg I OI Bakker Dennis D van Winden Vincent J C VJ Ras Nienke N Kemp Arjan C AC Cordfunke Robert A RA Dragan Irina I Deelder André M AM Kuijper Ed J EJ Corver Jeroen J Drijfhout Jan W JW van Leeuwen Hans C HC
Molecular & cellular proteomics : MCP 20140312 5
Bacterial secreted proteins constitute a biologically important subset of proteins involved in key processes related to infection such as adhesion, colonization, and dissemination. Bacterial extracellular proteases, in particular, have attracted considerable attention, as they have been shown to be indispensable for bacterial virulence. Here, we analyzed the extracellular subproteome of Clostridium difficile and identified a hypothetical protein, CD2830, as a novel secreted metalloprotease. Foll ...[more]