Association study of 15q14 and 15q25 with high myopia in the Han Chinese population.
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ABSTRACT:
SUBMITTER: Qiang Y
PROVIDER: S-EPMC4014749 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Association study of 15q14 and 15q25 with high myopia in the Han Chinese population.
Qiang Yu Y Li Wenjin W Wang Qingzhong Q He Kuanjun K Li Zhiqiang Z Chen Jianhua J Song Zhijian Z Qu Jia J Zhou Xiangtian X Qin Shengying S Shen Jiawei J Wen Zujia Z Ji Jue J Shi Yongyong Y
BMC genetics 20140427
<h4>Background</h4>Refractive errors and high myopia are the most common ocular disorders, and both of them are leading causes of blindness in the world. Recently, genetic association studies in European and Japanese population identified that common genetic variations located in 15q14 and 15q25 were associated with high myopia. To validate whether the same variations conferred risk to high myopia in the Han Chinese population, we genotyped 1,461 individuals (940 controls and 521 cases samples) ...[more]
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