Ontology highlight
ABSTRACT:
SUBMITTER: Emig-Agius D
PROVIDER: S-EPMC4016004 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Emig-Agius Dorothea D Olivieri Kevin K Pache Lars L Shih Hsin Ling HL Pustovalova Olga O Bessarabova Marina M Young John A T JA Chanda Sumit K SK Ideker Trey T
PloS one 20140509 5
Recent proteomic and genetic studies have aimed to identify a complete network of interactions between HIV and human proteins and genes. This HIV-human interaction network provides invaluable information as to how HIV exploits the host machinery and can be used as a starting point for further functional analyses. We integrated this network with complementary datasets of protein function and interaction to nominate human protein complexes with likely roles in viral infection. Based on our approac ...[more]