Ontology highlight
ABSTRACT:
SUBMITTER: Jones SE
PROVIDER: S-EPMC4018721 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Jones Sara E SE Paynich Mallory L ML Kearns Daniel B DB Knight Katherine L KL
Journal of immunology (Baltimore, Md. : 1950) 20140416 10
Host inflammatory responses against pathogenic organisms can be abrogated by commensals; however, the molecular mechanisms by which pathogenesis is prevented are still poorly understood. Previous studies demonstrated that administration of a single dose of Bacillus subtilis prevented disease and inflammation by the enteric mouse pathogen Citrobacter rodentium, which causes disease similar to the human pathogen enteropathogenic Escherichia coli. No protection was observed when an exopolysaccharid ...[more]