Ontology highlight
ABSTRACT:
SUBMITTER: Lorkowski M
PROVIDER: S-EPMC4019164 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Infection and immunity 20140407 6
The invasion of polarized epithelial cells by Salmonella enterica requires the cooperative activity of the Salmonella pathogenicity island 1 (SPI1)-encoded type III secretion system (T3SS) and the SPI4-encoded adhesin SiiE. The invasion of polarized cells is more efficient than that of nonpolarized cells, and we observed the formation of clusters of bacteria on infected cells. Here we demonstrate that the invasion of polarized cells is a highly cooperative activity. Using a novel live-cell imagi ...[more]