Divergent picobirnaviruses in human feces.
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ABSTRACT:
SUBMITTER: Ng TF
PROVIDER: S-EPMC4022810 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Publications
Divergent picobirnaviruses in human feces.
Ng Terry Fei Fan TF Vega Everardo E Kondov Nikola O NO Markey Christopher C Deng Xutao X Gregoricus Nicole N Vinjé Jan J Delwart Eric E
Genome announcements 20140515 3
The near-complete genomes of two picobirnaviruses (PBVs) in diarrheal stool samples, human picobirnaviruses D and E (HuPBV-D and -E), were genetically characterized. Their RNA-dependent RNA polymerase (RdRp) protein sequences had <66% identities to known PBVs. Due to a single nucleotide insertion, the open reading frame 2 (ORF2) in segment 1 of HuPBV-D was interrupted by a stop codon. A small stem-loop structure overlying the stop codon may result in translational readthrough into the rest of OR ...[more]
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