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Association study of X chromosome SNPs in attempted suicide.


ABSTRACT: We report the results of a high-density attempted suicide association study of the X chromosome, which genotyped 23,141 SNPs on 983 attempters and 1143 non-attempters and generated modest evidence for association for SH3KBP1 (P=1.07×10(-4)) and GRIA3 (P=4.01×10(-4)). These findings highlight the need for larger sample sets and meta-analytic approaches.

SUBMITTER: Jancic D 

PROVIDER: S-EPMC4023562 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature

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Association study of X chromosome SNPs in attempted suicide.

Jancic Dubravka D   Seifuddin Fayaz F   Zandi Peter P PP   Potash James B JB   Willour Virginia L VL  

Psychiatry research 20120704 2-3


We report the results of a high-density attempted suicide association study of the X chromosome, which genotyped 23,141 SNPs on 983 attempters and 1143 non-attempters and generated modest evidence for association for SH3KBP1 (P=1.07×10(-4)) and GRIA3 (P=4.01×10(-4)). These findings highlight the need for larger sample sets and meta-analytic approaches. ...[more]

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