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The roles of TGF? in the tumour microenvironment.


ABSTRACT: The influence of the microenvironment on tumour progression is becoming clearer. In this Review we address the role of an essential signalling pathway, that of transforming growth factor-?, in the regulation of components of the tumour microenvironment and how this contributes to tumour progression.

SUBMITTER: Pickup M 

PROVIDER: S-EPMC4025940 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature

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The roles of TGFβ in the tumour microenvironment.

Pickup Michael M   Novitskiy Sergey S   Moses Harold L HL  

Nature reviews. Cancer 20131017 11


The influence of the microenvironment on tumour progression is becoming clearer. In this Review we address the role of an essential signalling pathway, that of transforming growth factor-β, in the regulation of components of the tumour microenvironment and how this contributes to tumour progression. ...[more]

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