Cardiac (123)I-metaiodobenzylguanidine Scintigraphy in a Patient with Familial Parkinsonism with Parkin Gene Mutation.
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ABSTRACT:
SUBMITTER: Kim YD
PROVIDER: S-EPMC4027666 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
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Cardiac (123)I-metaiodobenzylguanidine Scintigraphy in a Patient with Familial Parkinsonism with Parkin Gene Mutation.
Kim Young-Do YD Song In-Uk IU Kim Joong-Seok JS Chung Sung-Woo SW Lee Kwang-Soo KS
Journal of movement disorders 20101030 2
A decreased cardiac (123)I-metaiodobenzylguanidine ((123)I-MIBG) uptake has been used as a powerful tool to identify Lewy body disease, such as idiopathic parkinson's disease (IPD). We performed cardiac (123)I-MIBG scintigraphy in patient with autosomal recessive juvenile parkinsonism (ARJP) with parkin gene mutation (PARK2). The findings showed normal cardiac (123)I-MIBG uptake. Therefore, although the clinical features of ARJP are sometimes quite similar to those of late-onset IPD, cardiac (12 ...[more]
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