Ontology highlight
ABSTRACT:
SUBMITTER: Rodriguez-Nunez I
PROVIDER: S-EPMC4028400 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Rodríguez-Nunez Iván I Wcisel Dustin J DJ Litman Gary W GW Yoder Jeffrey A JA
Developmental and comparative immunology 20140215 1
Five large multigene families encoding innate-type immune receptors that are comprised of immunoglobulin domains have been identified in bony fish, of which four do not possess definable mammalian orthologs. The members of some of the multigene families exhibit unusually extensive patterns of divergence and the individual family members demonstrate marked variation in interspecific comparisons. As a group, the gene families reveal striking differences in domain type and content, mechanisms of in ...[more]