Ontology highlight
ABSTRACT:
SUBMITTER: Liao XX
PROVIDER: S-EPMC4028872 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Liao Xin-xin XX Zhan Zi-xiong ZX Luo Ying-ying YY Li Kai K Wang Jun-ling JL Guo Ji-feng JF Yan Xin-xiang XX Xia Kun K Tang Bei-sha BS Shen Lu L
BMC neurology 20131211
<h4>Background</h4>Recent studies suggest that epigenetic factors may play an important role in the pathogenesis of Parkinson's disease (PD). In our previous work, we sequenced the exomes of sixteen patients from eight Chinese PD families using whole exome sequencing technology, consequently three patients from different pedigrees were found sharing the variant c.1460C > T (rs150689919) in the coding region of the Tet methyl cytosine dioxygenase 1 (TET1) gene.<h4>Methods</h4>In order to evaluate ...[more]