Ontology highlight
ABSTRACT:
SUBMITTER: Wesmiller SW
PROVIDER: S-EPMC4028967 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Wesmiller Susan W SW Henker Richard A RA Sereika Susan M SM Donovan Heidi S HS Meng Li L Gruen Gary S GS Tarkin Ivan S IS Conley Yvette P YP
Biological research for nursing 20120620 4
The CYP2D6 gene encodes for an enzyme that is involved in the metabolism of more than 25% of all medications, including many opioids and antiemetics. It may contribute to the risk of postoperative nausea and vomiting (PONV), a common surgical complication. However, little research has been conducted in this area. The purpose of this study was to explore the association of CYP2D6 genotypes with PONV in adult surgical trauma patients. Data from 112 patients (28% female) with single extremity fract ...[more]