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Antigen-responsive, microfluidic valves for single use diagnostics.


ABSTRACT: The growing need for medical diagnostics in resource limited settings is driving the development of simple, standalone immunoassay devices. A capillary flow device using polymerization based amplification is capable of blocking a microfluidic channel in response to target biomaterials, enabling multiple modes of detection that require little or no supplemental instrumentation.

SUBMITTER: Berron BJ 

PROVIDER: S-EPMC4030428 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature

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Antigen-responsive, microfluidic valves for single use diagnostics.

Berron Brad J BJ   May Allison M AM   Zheng Zheng Z   Balasubramaniam Vivek V   Bowman Christopher N CN  

Lab on a chip 20120104 4


The growing need for medical diagnostics in resource limited settings is driving the development of simple, standalone immunoassay devices. A capillary flow device using polymerization based amplification is capable of blocking a microfluidic channel in response to target biomaterials, enabling multiple modes of detection that require little or no supplemental instrumentation. ...[more]

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