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Magnetic Two-Way Valves for Paper-Based Capillary-Driven Microfluidic Devices.

ABSTRACT: This article presents a magnetically actuated two-way, three-position (+, 0, -), paper-based microfluidic valve that includes a neutral position (0)-the first of its kind. The system is highly robust, customizable, and fully automated. The advent of a neutral position and the ability to precisely control switching frequencies establish a new platform for highly controlled fluid flows in paper-based wicking microfluidic devices. The potential utility of these valves is demonstrated in automated, programmed, patterning of dyed liquids in a wicking device akin to a colorimetric assay but with a programmed fluid/reagent delivery. These valves are fabricated using facile methods and thus remain cost-effective for adoption into affordable point-of-care/bioanalytical devices.

SUBMITTER: Fratzl M

PROVIDER: S-EPMC6641529 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature

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Magnetic Two-Way Valves for Paper-Based Capillary-Driven Microfluidic Devices.

Fratzl Mario M Chang Boyce S BS Oyola-Reynoso Stephanie S Blaire Guillaume G Delshadi Sarah S Devillers Thibaut T Ward Thomas T Dempsey Nora M NM Bloch Jean-Francis JF Thuo Martin M MM

ACS omega 20180220 2

This article presents a magnetically actuated two-way, three-position (+, 0, -), paper-based microfluidic valve that includes a neutral position (0)-the first of its kind. The system is highly robust, customizable, and fully automated. The advent of a neutral position and the ability to precisely control switching frequencies establish a new platform for highly controlled fluid flows in paper-based wicking microfluidic devices. The potential utility of these valves is demonstrated in automated, ...[more]

PMID: 31458514

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