Ontology highlight
ABSTRACT:
SUBMITTER: Klorin G
PROVIDER: S-EPMC4030604 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Klorin Geula G Rozenblum Ester E Glebov Oleg O Walker Robert L RL Park Yoonsoo Y Meltzer Paul S PS Kirsch Ilan R IR Kaye Frederic J FJ Roschke Anna V AV
Cancer genetics 20130501 5
High-resolution oligonucleotide array comparative genomic hybridization (aCGH) and spectral karyotyping (SKY) were applied to a panel of malignant mesothelioma (MMt) cell lines. SKY has not been applied to MMt before, and complete karyotypes are reported based on the integration of SKY and aCGH results. A whole genome search for homozygous deletions (HDs) produced the largest set of recurrent and non-recurrent HDs for MMt (52 recurrent HDs in 10 genomic regions; 36 non-recurrent HDs). For the fi ...[more]