Network identification of hormonal regulation.
Ontology highlight
ABSTRACT:
SUBMITTER: Vis DJ
PROVIDER: S-EPMC4031081 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Network identification of hormonal regulation.
Vis Daniel J DJ Westerhuis Johan A JA Hoefsloot Huub C J HC Roelfsema Ferdinand F van der Greef Jan J Hendriks Margriet M W B MM Smilde Age K AK
PloS one 20140522 5
Relations among hormone serum concentrations are complex and depend on various factors, including gender, age, body mass index, diurnal rhythms and secretion stochastics. Therefore, endocrine deviations from healthy homeostasis are not easily detected or understood. A generic method is presented for detecting regulatory relations between hormones. This is demonstrated with a cohort of obese women, who underwent blood sampling at 10 minute intervals for 24-hours. The cohort was treated with bromo ...[more]
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