A new era of GPCR structural and chemical biology.
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ABSTRACT:
SUBMITTER: Granier S
PROVIDER: S-EPMC4031315 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Publications
A new era of GPCR structural and chemical biology.
Granier Sébastien S Kobilka Brian B
Nature chemical biology 20120718 8
G protein-coupled receptors (GPCRs) are versatile molecular machines that regulate the majority of physiological responses to chemically diverse hormones and neurotransmitters. Recent breakthroughs in structural studies have advanced our understanding of GPCR signaling, particularly the selectivity of ligand recognition and receptor activation of G proteins. ...[more]
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