Ontology highlight
ABSTRACT:
SUBMITTER: Ye D
PROVIDER: S-EPMC4031611 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Nature chemistry 20140428 6
Directed self-assembly of small molecules in living systems could enable a myriad of applications in biology and medicine, and already this has been used widely to synthesize supramolecules and nano/microstructures in solution and in living cells. However, controlling the self-assembly of synthetic small molecules in living animals is challenging because of the complex and dynamic in vivo physiological environment. Here we employ an optimized first-order bioorthogonal cyclization reaction to con ...[more]