Ontology highlight
ABSTRACT:
SUBMITTER: Pan Y
PROVIDER: S-EPMC4031949 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Pan Yi Y Zhou Haihong H Mahsut Ablatt A Rohm Rory J RJ Berejnaia Olga O Price Olga O Chen Ying Y Castro-Perez Jose J Lassman Michael E ME McLaren David D Conway James J Jensen Kristian K KK Thomas Tiffany T Reyes-Soffer Gissette G Ginsberg Henry N HN Gutstein David E DE Cleary Michele M Previs Stephen F SF Roddy Thomas P TP
Journal of lipid research 20140402 6
LC/MS quantification of multiple plasma proteins that differ by several orders of magnitude in concentration from a single sample is challenging. We present a strategy that allows the simultaneous determination of the concentration and turnover kinetics of higher and lower abundant proteins from a single digestion mixture. Our attention was directed at a cluster of proteins that interact to affect the absorption and interorgan lipid trafficking. We demonstrate that apos involved in TG metabolism ...[more]