The past, present and future of neutralizing antibodies for hepatitis C virus.
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ABSTRACT:
SUBMITTER: Ball JK
PROVIDER: S-EPMC4034163 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Publications
The past, present and future of neutralizing antibodies for hepatitis C virus.
Ball Jonathan K JK Tarr Alexander W AW McKeating Jane A JA
Antiviral research 20140226
Hepatitis C virus (HCV) is a major cause of liver disease and hepatocellular carcinoma worldwide. HCV establishes a chronic infection in the majority of cases. However, some individuals clear the virus, demonstrating a protective role for the host immune response. Although new all-oral drug combinations may soon replace traditional ribavirin-interferon therapy, the emerging drug cocktails will be expensive and associated with side-effects and resistance, making a global vaccine an urgent priorit ...[more]
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