Ontology highlight
ABSTRACT:
SUBMITTER: DeMichele-Sweet MA
PROVIDER: S-EPMC4034371 | biostudies-literature | 2014 Mar
REPOSITORIES: biostudies-literature
Current genetic medicine reports 20140301 1
Psychosis occurs in approximately half of patients with Alzheimer disease (AD with psychosis, AD+P). AD+P patients have more rapid cognitive decline, greater behavioral symptoms, and higher mortality than do AD patients without psychosis. Studies in three independent cohorts have shown that psychosis in AD aggregates in families, with estimated heritability of 29.5 - 60.8%. These findings have motivated studies to investigate and uncover the genes responsible for the development of psychosis, wi ...[more]