Ontology highlight
ABSTRACT:
SUBMITTER: Volfovsky N
PROVIDER: S-EPMC403649 | biostudies-literature | 2003 Jun
REPOSITORIES: biostudies-literature
Volfovsky Natalia N Haas Brian J BJ Salzberg Steven L SL
Genome research 20030601 6A
Very short exons, also known as micro-exons, occur in large numbers in some eukaryotic genomes. Existing annotation tools have a limited ability to recognize these short sequences, which range in length up to 25 bp. Here, we describe a computational method for the identification of micro-exons using near-perfect alignments between cDNA and genomic DNA sequences. Using this method, we detected 319 micro-exons in 4 complete genomes, of which 224 were previously unknown, human (170), the nematode C ...[more]