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Epidemiologic trends in head and neck cancer and aids in diagnosis.

ABSTRACT: Head and neck squamous cell carcinoma is the sixth most common cancer worldwide predominately associated with tobacco use. Changing cause and increased incidence in oropharyngeal carcinomas is associated with high-risk types of human papilloma virus and has an improved survival. Optical devices may augment visual oral examination; however, their lack of specificity still warrants tissue evaluation/biopsy. Histologic factors of oral carcinomas are critical for patient management and prognostic determination. Clinical biomarkers are still needed to improve early detection, predict malignant transformation, and optimize therapies.

SUBMITTER: Vigneswaran N

PROVIDER: S-EPMC4040236 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature

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Epidemiologic trends in head and neck cancer and aids in diagnosis.

Vigneswaran Nadarajah N Williams Michelle D MD

Oral and maxillofacial surgery clinics of North America 20140501 2

Head and neck squamous cell carcinoma is the sixth most common cancer worldwide predominately associated with tobacco use. Changing cause and increased incidence in oropharyngeal carcinomas is associated with high-risk types of human papilloma virus and has an improved survival. Optical devices may augment visual oral examination; however, their lack of specificity still warrants tissue evaluation/biopsy. Histologic factors of oral carcinomas are critical for patient management and prognostic de ...[more]

PMID: 24794262

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