Ontology highlight
ABSTRACT:
SUBMITTER: Giansanti MG
PROVIDER: S-EPMC404041 | biostudies-literature | 2004 May
REPOSITORIES: biostudies-literature
Giansanti Maria Grazia MG Farkas Rebecca M RM Bonaccorsi Silvia S Lindsley Dan L DL Wakimoto Barbara T BT Fuller Margaret T MT Gatti Maurizio M
Molecular biology of the cell 20040305 5
We have used Drosophila male meiosis as a model system for genetic dissection of the cytokinesis mechanism. Drosophila mutants defective in meiotic cytokinesis can be easily identified by their multinucleate spermatids. Moreover, the large size of meiotic spindles allows characterization of mutant phenotypes with exquisite cytological resolution. We have screened a collection of 1955 homozygous mutant male sterile lines for those with multinucleate spermatids, and thereby identified mutations in ...[more]