Ontology highlight
ABSTRACT:
SUBMITTER: Rubinstein L
PROVIDER: S-EPMC4041441 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Rubinstein Linda L Ungar Lior L Harari Yaniv Y Babin Vera V Ben-Aroya Shay S Merenyi Gabor G Marjavaara Lisette L Chabes Andrei A Kupiec Martin M
Nucleic acids research 20140411 10
Genome-wide systematic screens in yeast have uncovered a large gene network (the telomere length maintenance network or TLM), encompassing more than 400 genes, which acts coordinatively to maintain telomere length. Identifying the genes was an important first stage; the next challenge is to decipher their mechanism of action and to organize then into functional groups or pathways. Here we present a new telomere-length measuring program, TelQuant, and a novel assay, telomere length kinetics assay ...[more]