Ontology highlight
ABSTRACT:
SUBMITTER: Yu X
PROVIDER: S-EPMC4045614 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Proceedings of the ... SIAM International Conference on Data Mining. SIAM International Conference on Data Mining 20130101
HIV rapidly evolves drug resistance in response to antiviral drugs used in AIDS therapy. Estimating the specific resistance of a given strain of HIV to individual drugs from sequence data has important benefits for both the therapy of individual patients and the development of novel drugs. We have developed an accurate classification method based on the sparse representation theory, and demonstrate that this method is highly effective with HIV-1 protease. The protease structure is represented us ...[more]