Ontology highlight
ABSTRACT:
SUBMITTER: Kong M
PROVIDER: S-EPMC7010952 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Kong Meng M Zhang Yusen Y Xu Da D Chen Wei W Dehmer Matthias M
Frontiers in genetics 20200204
The task of predicting protein-protein interactions (PPIs) has been essential in the context of understanding biological processes. This paper proposes a novel computational model namely FCTP-WSRC to predict PPIs effectively. Initially, combinations of the F-vector, composition (C) and transition (T) are used to map each protein sequence onto numeric feature vectors. Afterwards, an effective feature extraction method PCA (principal component analysis) is employed to reconstruct the most discrimi ...[more]