Ontology highlight
ABSTRACT:
SUBMITTER: Timsina YN
PROVIDER: S-EPMC4046774 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20140417 17
In the asymmetric hydrovinylation (HV) of an E/Z-mixture of a prototypical 1,3-diene with (S,S)-(DIOP)CoCl2 or (S,S)-(BDPP)CoCl2 catalyst in the presence of Me3Al, the (E)-isomer reacts significantly faster, leaving behind the Z-isomer intact at the end of the reaction. The presumed [LCo-H](+)-intermediate, especially when L is a large-bite angle ligand, similar to DIOP and BDPP, promote an unusual isomerization of (E/Z)-mixtures of 1,3-dienes to isomerically pure Z-isomers. A mechanism that inv ...[more]