A molecular revolution in uveal melanoma: implications for patient care and targeted therapy.
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ABSTRACT:
SUBMITTER: Harbour JW
PROVIDER: S-EPMC4047132 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Publications
A molecular revolution in uveal melanoma: implications for patient care and targeted therapy.
Harbour J William JW Chao Daniel L DL
Ophthalmology 20140128 6
Uveal melanoma is the most common primary intraocular malignancy and has a strong propensity for fatal metastasis. Recent advances in the molecular genetics of uveal melanoma are revolutionizing our understanding of this cancer and the care of patients. The development of a new molecular classification of uveal melanoma based on a widely available 15-gene expression profile now allows patients at high risk of metastasis to be identified early so that individualized management can be offered. The ...[more]
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