Ontology highlight
ABSTRACT:
SUBMITTER: Dunworth WP
PROVIDER: S-EPMC4047637 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Circulation research 20131011 1
<h4>Rationale</h4>The emergence of lymphatic endothelial cells (LECs) seems to be highly regulated during development. Although several factors that promote the differentiation of LECs in embryonic development have been identified, those that negatively regulate this process are largely unknown.<h4>Objective</h4>Our aim was to delineate the role of bone morphogenetic protein (BMP) 2 signaling in lymphatic development.<h4>Methods and results</h4>BMP2 signaling negatively regulates the formation o ...[more]