Ontology highlight
ABSTRACT:
SUBMITTER: Hosseinizadeh A
PROVIDER: S-EPMC4052863 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Hosseinizadeh A A Schwander P P Dashti A A Fung R R D'Souza R M RM Ourmazd A A
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20140701 1647
The advent of the X-ray free-electron laser (XFEL) has made it possible to record diffraction snapshots of biological entities injected into the X-ray beam before the onset of radiation damage. Algorithmic means must then be used to determine the snapshot orientations and thence the three-dimensional structure of the object. Existing Bayesian approaches are limited in reconstruction resolution typically to 1/10 of the object diameter, with the computational expense increasing as the eighth power ...[more]