Genome-wide miRNA seeds prediction in Archaea.
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ABSTRACT:
SUBMITTER: Wang S
PROVIDER: S-EPMC4053300 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Genome-wide miRNA seeds prediction in Archaea.
Wang Shengqin S Xu Yuming Y Lu Zuhong Z
Archaea (Vancouver, B.C.) 20140514
Growing evidence indicates that miRNA genes exist in the archaeal genome, though the functional role of such noncoding RNA remains unclear. Here, we integrated the phylogenetic information of available archaeal genomes to predict miRNA seeds (typically defined as the 2-8 nucleotides of mature miRNAs) on the genomic scale. Finally, we found 2649 candidate seeds with significant conservation signal. Eleven of 29 unique seeds from previous study support our result (P value <0.01), which demonstrate ...[more]
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