Ontology highlight
ABSTRACT:
SUBMITTER: Nonnenmann J
PROVIDER: S-EPMC4054423 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Nonnenmann Julia J Stirner Renate R Roider Julia J Jung Maria C MC Schrödl Kathrin K Bogner Johannes R JR Draenert Rika R
Journal of virology 20140416 13
Myeloid-derived suppressor cells (MDSC) are immature myeloid cells with immunosuppressive function. Compared to the level in healthy controls (HC), no elevation of MDSC in chronic hepatitis C (cHEP-C) patients was found, and there was no difference in MDSC based on genotype or viral load (P > 0.25). Moreover, MDSC of cHEP-C patients inhibited CD8 T cell function as efficiently as MDSC of HC did. Since we detected neither quantitative nor qualitative differences in MDSC of cHEP-C patients relativ ...[more]