In situ imaging in C. elegans reveals developmental regulation of microtubule dynamics.
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ABSTRACT:
SUBMITTER: Lacroix B
PROVIDER: S-EPMC4062621 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Publications
In situ imaging in C. elegans reveals developmental regulation of microtubule dynamics.
Lacroix Benjamin B Bourdages Karine G KG Dorn Jonas F JF Ihara Shinji S Sherwood David R DR Maddox Paul S PS Maddox Amy S AS
Developmental cell 20140401 2
Microtubules (MTs) are cytoskeletal polymers that undergo dynamic instability, the stochastic transition between growth and shrinkage phases. MT dynamics are required for diverse cellular processes and, while intrinsic to tubulin, are highly regulated. However, little is known about how MT dynamics facilitate or are regulated by tissue biogenesis and differentiation. We imaged MT dynamics in a smooth muscle-like lineage in intact developing Caenorhabditis elegans. All aspects of MT dynamics chan ...[more]
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