MAGI: Methylation analysis using genome information.
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ABSTRACT:
SUBMITTER: Baumann DD
PROVIDER: S-EPMC4063829 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Publications
MAGI: Methylation analysis using genome information.
Baumann Douglas D DD Doerge R W RW
Epigenetics 20140331 5
By incorporating annotation information into the analysis of next-generation sequencing DNA methylation data, we provide an improvement in performance over current testing procedures. Methylation analysis using genome information (MAGI) is applicable for both unreplicated and replicated data, and provides an effective analysis for studies with low sequencing depth. When compared with current tests, the annotation-informed tests provide an increase in statistical power and offer a significance-ba ...[more]
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