Dataset Information

Circulation time measurement from sleep studies in patients with obstructive sleep apnea.

ABSTRACT:

Introduction

Lung to finger circulation time (LFCT) can be estimated from polysomnography (PSG) in the presence of an apneic event by using oxygen as an indicator and a finger as the site of detection. The purpose of this study was to refine the methodology of LFCT measurement and to compare LFCT in patients with obstructive sleep apnea (OSA) with and without heart failure (HF).

Methods

In a retrospective manner, 10 LFCT measurements per patient were made from the PSG in 171 consecutive patients with a diagnosis of OSA who were divided into two groups: (a) those with a clinical history of underlying HF (N = 42) and (b) those without HF (N = 129). Mean values were compared between the two groups. We also examined associations of LFCT with various factors in each group and the combined group separately using multiple regression analysis.

Results

Gender and age were significantly associated with LFCT in patients with OSA alone. Use of ?-blockers was associated with LFCT in the group with OSA with HF. Among the entire cohort, HF, ?-blocker, gender, and age were found to be significantly associated with LFCT. The presence of HF was the strongest predictor of a prolonged LFCT (adjusted mean LFCT: OSA only = 18.5 [95% CI: 17.2-19.7 sec] vs. OSA with HF = 26.1 [95% CI: 24.3-28.0 sec], p < 0.0001).

Conclusion

LFCT can be reliably measured and is prolonged in patients with OSA and underlying HF. LFCT based on PSG may be a useful marker for detection of coexisting HF in patients with OSA.

SUBMITTER: Kwon Y

PROVIDER: S-EPMC4067439 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature

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Publications

Circulation time measurement from sleep studies in patients with obstructive sleep apnea.

Kwon Younghoon Y Khan Talha T Pritzker Marc M Iber Conrad C

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20140715 7

<h4>Introduction</h4>Lung to finger circulation time (LFCT) can be estimated from polysomnography (PSG) in the presence of an apneic event by using oxygen as an indicator and a finger as the site of detection. The purpose of this study was to refine the methodology of LFCT measurement and to compare LFCT in patients with obstructive sleep apnea (OSA) with and without heart failure (HF).<h4>Methods</h4>In a retrospective manner, 10 LFCT measurements per patient were made from the PSG in 171 conse ...[more]

PMID: 25024653

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Dataset Information

Circulation time measurement from sleep studies in patients with obstructive sleep apnea.

Introduction

Methods

Results

Conclusion

Publications

Circulation time measurement from sleep studies in patients with obstructive sleep apnea.

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