Ontology highlight
ABSTRACT:
SUBMITTER: Liu T
PROVIDER: S-EPMC4067619 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Liu Tianyu T Liu Xiaogang X Spring David R DR Qian Xuhong X Cui Jingnan J Xu Zhaochao Z
Scientific reports 20140624
Viscosity is a fundamental physical parameter that influences diffusion in biological processes. The distribution of intracellular viscosity is highly heterogeneous, and it is challenging to obtain a full map of cellular viscosity with detailed organelle information. In this work, we report 1 as the first fluorescent viscosity probe which is able to quantitatively map cellular viscosity with detailed organelle information based on the PET mechanism. This probe exhibited a significant ratiometric ...[more]