Effects of ovarian hormones on internal circadian organization in rats.
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ABSTRACT:
SUBMITTER: Murphy ZC
PROVIDER: S-EPMC4076364 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
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Effects of ovarian hormones on internal circadian organization in rats.
Murphy Zachary C ZC Pezuk Pinar P Menaker Michael M Sellix Michael T MT
Biology of reproduction 20130815 2
The circadian clock in the suprachiasmatic nucleus (SCN) of the hypothalamus is the central pacemaker driving rhythms in endocrine physiology. Gonadal steroid hormones affect behavioral rhythms and clock gene expression. However, the impact of fluctuating ovarian steroid levels during the estrous cycle on internal circadian organization remains to be determined. Further, it is not known if steroid hormone depletion, as in menopause, affects the timing system. To determine the influence of estrou ...[more]
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