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Homochiral BINOL-based macrocycles with ?-electron-rich, electron-withdrawing or extended spacing units as receptors for C60.

ABSTRACT: The "one-pot" synthesis of several homochiral macrocycles has been achieved by using ?-electron-rich, electron-deficient or extended aromatic dicarboxylic acids in combination with an axially-chiral dibenzylic alcohol, derived from enantiomerically-pure BINOL. Two series of cyclic adducts with average molecular D 2 and D 3 molecular symmetries, respectively, have been isolated in pure forms. Their yields and selectivities deviate substantially from statistical distributions. NMR and CD spectroscopic methods are efficient and functional in order to highlight the variability of shapes of the covalent macrocyclic frameworks. The larger D 3 cyclic adducts exhibit recognition properties towards C60 in toluene solutions (up to log K a = 3.2) with variable stoichiometries and variable intensities of the charge-tranfer band upon complexation.

SUBMITTER: Caricato M

PROVIDER: S-EPMC4077419 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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Homochiral BINOL-based macrocycles with π-electron-rich, electron-withdrawing or extended spacing units as receptors for C60.

Caricato Marco M González Silvia Díez SD Arandia Ariño Idoia I Pasini Dario D

Beilstein journal of organic chemistry 20140606

The "one-pot" synthesis of several homochiral macrocycles has been achieved by using π-electron-rich, electron-deficient or extended aromatic dicarboxylic acids in combination with an axially-chiral dibenzylic alcohol, derived from enantiomerically-pure BINOL. Two series of cyclic adducts with average molecular D 2 and D 3 molecular symmetries, respectively, have been isolated in pure forms. Their yields and selectivities deviate substantially from statistical distributions. NMR and CD spectrosc ...[more]

PMID: 24991283

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