Influence of Mifepristone in Induction Time for Terminations in the Second and Third Trimester.

ABSTRACT: Termination of pregnancy after the first trimester is generally carried out by medical induction. Question: The aim of this study is to investigate the effect of mifepristone before administration of the prostaglandin derivative on induction time. Material and Methods: We analysed 333 medically indicated terminations after the first trimester under the terms of § 218 a Para. 2 of the German Criminal Code, in which the prostaglandin derivatives misoprostol, gemeprost or dinoprostone were administered with or without pre-treatment with 600 mg of mifepristone. The time interval between the initial administration of prostaglandin and delivery was investigated. Using uni- and multivariate regression analysis, the effect of maternal age, body mass index, gravidity and parity, previ

SUBMITTER: Hoopmann M 

PROVIDER: S-EPMC4078152 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature