Ontology highlight
ABSTRACT:
SUBMITTER: Tan K
PROVIDER: S-EPMC4078742 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Methods in molecular biology (Clifton, N.J.) 20140101
The growth of diffraction-quality single crystals is of primary importance in protein X-ray crystallography. Chemical modification of proteins can alter their surface properties and crystallization behavior. The Midwest Center for Structural Genomics (MCSG) has previously reported how reductive methylation of lysine residues in proteins can improve crystallization of unique proteins that initially failed to produce diffraction-quality crystals. Recently, this approach has been expanded to includ ...[more]