Ontology highlight
ABSTRACT:
SUBMITTER: Yu B
PROVIDER: S-EPMC4079107 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Yu Bing B Zheng Yan Y Alexander Danny D Manolio Teri A TA Alonso Alvaro A Nettleton Jennifer A JA Boerwinkle Eric E
Genetic epidemiology 20130811 8
Both the prevalence and incidence of heart failure (HF) are increasing, especially among African Americans, but no large-scale, genome-wide association study (GWAS) of HF-related metabolites has been reported. We sought to identify novel genetic variants that are associated with metabolites previously reported to relate to HF incidence. GWASs of three metabolites identified previously as risk factors for incident HF (pyroglutamine, dihydroxy docosatrienoic acid, and X-11787, being either hydroxy ...[more]