Protective effect of Dl-3n-butylphthalide on learning and memory impairment induced by chronic intermittent hypoxia-hypercapnia exposure.
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ABSTRACT:
SUBMITTER: Min JJ
PROVIDER: S-EPMC4080197 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
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Protective effect of Dl-3n-butylphthalide on learning and memory impairment induced by chronic intermittent hypoxia-hypercapnia exposure.
Min Jing-jing JJ Huo Xin-long XL Xiang Ling-yun LY Qin Yan-qing YQ Chai Ke-qin KQ Wu Bin B Jin Lu L Wang Xiao-tong XT
Scientific reports 20140703
Cognitive impairment is a common finding in patients with chronic obstructive pulmonary disease (COPD), but little attention has been focused on therapeutic intervention for this complication. Chronic intermittent hypoxia hypercapnia (CIHH) exposure is considered to be responsible for the pathogenesis of COPD. Dl-3n-Butylphthalide (NBP), extracted from Apium graveolens Linn, has displayed a broad spectrum of neuroprotective properties. Our study aimed to investigate the potential of NBP on CIHH- ...[more]
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