Ontology highlight
ABSTRACT:
SUBMITTER: Wu F
PROVIDER: S-EPMC6991645 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Wu Fangfang F Xu Ke K Xu Kebin K Teng Chenhuai C Zhang Man M Xia Leilei L Zhang Kairui K Liu Lei L Chen Zaifeng Z Xiao Jian J Wu Yanqing Y Zhang Hongyu H Chen Daqing D
Journal of cellular and molecular medicine 20191216 2
Blood-brain barrier (BBB) disruption and neuronal apoptosis are important pathophysiological processes after traumatic brain injury (TBI). In clinical stroke, Dl-3n-butylphthalide (Dl-NBP) has a neuroprotective effect with anti-inflammatory, anti-oxidative, anti-apoptotic and mitochondrion-protective functions. However, the effect and molecular mechanism of Dl-NBP for TBI need to be further investigated. Here, we had used an animal model of TBI and SH-SY5Y/human brain microvascular endothelial c ...[more]