Ontology highlight
ABSTRACT:
SUBMITTER: Ra JS
PROVIDER: S-EPMC4083076 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Ra Jae-Sun JS Shin Hyun-Hee HH Kang Sebyung S Do Yoonkyung Y
Clinical and experimental vaccine research 20140620 2
<h4>Purpose</h4>Protein cages are promising nanoplatform candidates for efficient delivery systems due to their homogenous size and structure with high biocompatibility and biodegradability. In this study, we investigate the potential of lumazine synthase protein cage as an antigen delivery system to dendritic cells (DCs), which induce antigen-specific T cell proliferation.<h4>Materials and methods</h4>Ovalbumin (OVA) peptides OT-1 (SIINFEKL) and OT-2 (ISQAVHAAHAEINEAGR) were genetically inserte ...[more]